Dietary interventions with n-3 fatty acids or probiotics targeting post-myocardial infarction depression

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Dietary interventions with n-3 fatty acids or probiotics targeting post-myocardial infarction depression.

In this issue of the British Journal of Nutrition, Gilbert et al. describe attenuation of post-myocardial infarction (MI) depression by dietary supplementation with n-3 fatty acids or probiotics in a rat model. This paper indicates the importance of dietary intervention to avoid post-MI depression. Previously, it was shown that a high-PUFA diet enriched with n-3 fatty acids or a low-PUFA diet e...

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N-3 fatty acids: priority for post-myocardial infarction clinical trials.

Alarge body of data points to potential benefits of N-3 polyunsaturated fatty acids in reducing the risk of cardiovascular disease (CVD).1 Available data suggest that higher intakes of N-3 fatty acids will reduce various forms of CVD, especially sudden cardiovascular death. These data derive from laboratory animal studies, epidemiological data, metabolic studies, and smaller clinical trials. Th...

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Depression post-myocardial infarction.

Van Melle et al (2007) reported that cardiac prognosis post-myocardial infarction was not improved by antidepressant treatment (MIND–IT trial). The SADHART and ENRICHD trials reported similar findings and Carney & Freedland (2007), in their commentary in the same issue, suggest these negative findings are a result of insufficient statistical power in the trials. These results are disappointing ...

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n-3 Fatty Acids, Ventricular Arrhythmia–Related Events, and Fatal Myocardial Infarction in Postmyocardial Infarction Patients With Diabetes

OBJECTIVE We carried out a secondary analysis in high-risk patients with a previous myocardial infarction (MI) and diabetes in the Alpha Omega Trial. We tested the hypothesis that in these patients an increased intake of the n-3 fatty acids eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and α-linolenic acid (ALA) will reduce the incidence of ventricular arrhythmias and fatal MI. RES...

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ژورنال

عنوان ژورنال: British Journal of Nutrition

سال: 2013

ISSN: 0007-1145,1475-2662

DOI: 10.1017/s0007114512004254